1921
Volume 14, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Summary and Conclusions

A previously sensitive Chesson strain of was made resistant to chlorguanide by the stepwise use of increasing subcurative dosages.

Two volunteers medicated with CI-501 (5 mg/kg body weight) two days before challenge, and an untreated control, were exposed to the bites of infected with this resistant Chesson strain of . The two medicated volunteers as well as the control developed infections with no significant differences in the prepatent period or the clinical course.

The results indicate that CI-501 has no demonstrable effect on the Chesson strain of once resistance to the parent compound, chlorguanide, has been induced.

Loading

Article metrics loading...

The graphs shown below represent data from March 2017
/content/journals/10.4269/ajtmh.1965.14.922
1965-11-01
2019-09-17
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1965.14.922
Loading

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error