1921
Volume 14, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
USD

Abstract

Summary

Qualitative differences in host response to infection were observed in mice, multimammate rats, hamsters and gerbils.

Central necrosis within granulomas and hepatic parenchymal necrosis were most frequent in mice. The Hoeppli phenomenon was frequently observed about eggs in the multimammate rat but was not seen in other species. Granulomas in the hamster liver were characteristically histiocytic while those in the gerbil liver often contained numerous mast cells.

Extreme dilatation of peripheral hepatic lymphatics was frequent in multimammate rats but uncommon in other species.

Amyloidosis was a frequent complication of prolonged infection in hamsters. Peripheral edema, ascites and pleural effusions in this species were secondary to renal amyloidosis.

Marked hyperplasia of bile ducts was observed only in mice. Fibrosis about these ducts was present in many mice with prolonged infections.

Portal fibrosis and pylephlebitis were more marked in mice than in other species and were most marked in C3H mice. The resemblance of portal fibrosis to the pipestem fibrosis of human hepatic schistosomiasis was slight.

Direct or indirect evidence of worm death was seen occasionally in mice with prolonged infections but was not noted in other species.

Loading

Article metrics loading...

/content/journals/10.4269/ajtmh.1965.14.227
1965-03-01
2017-09-20
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1965.14.227
Loading

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error