1921
Volume 13, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

Summary

Studies on heat- and formalin-inactivated vaccines prepared from Asian and El Tor strains and tested in monkeys for agglutinating antibody production indicated that El Tor vaccines were antigenic and could be administered safely to these animals. Sera from monkeys vaccinated with both types of El Tor vaccines showed higher agglutinating antibodies against Ogawa subtype El Tor antigens than did sera from monkeys vaccinated with Asian vaccines. Formalin-inactivated El Tor vaccines used in this study retained slight residual hemolytic activity characteristic of El Tor vibrios but in heat inactivated vaccines, this property was lost.

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/content/journals/10.4269/ajtmh.1964.13.708
1964-09-01
2017-09-23
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