Volume 13, Issue 1_Part_2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


Dr. McGhee has presented experimental evidence that ducklings infected with and given sub-curative quinine treatment suffer from an anemia that differs from the anemias resulting from simple blood loss, or from infection with . In this anemia the radical reduction of polychromatophil erythroblasts seemed to be associated with the loss of this cell in the bone marrow. In discussing possible causative mechanisms for this anemia, it was suggested that these cellular elements might have been destroyed by an auto-immune process.

The implication here is that the association of host cell, parasite, and drug form an antigen complex that will sensitize ducklings and that the resulting antibodies react with and incapacitate, or destroy the erythroblast tissues of marrow. It would be of interest to determine whether or not a similar anemia would result in normal ducklings following passive transplant of humoral or cellular elements from -infected and quinine-treated ducklings, after artificial blood loss, which would normally make erythroblasts evident in the peripheral blood of the recipient animals.


Article metrics loading...

The graphs shown below represent data from March 2017
Loading full text...

Full text loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error