1921
Volume 10, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

Summary

The in vitro and in vivo amebicidal activities of eight new synthetic N,N′-bis(dichloroacetyl)diamines are reported. These compounds are amebicidal in vitro against in concentrations of 1 part in 1 million to as low as 1 part in 50 million. In vivo amebicidal activity was evaluated in hamsters spontaneously infected with . The compounds discussed are highly amebicidal; their calculated ED values are in the range of 0.7 to 2.5 mg/kg/day when given for 4 days.

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/content/journals/10.4269/ajtmh.1961.10.503
1961-07-01
2017-09-22
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