Volume 9, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



The relative sensitivity of four intradermal and five serologic procedures was determined on patients with an unequivocal diagnosis of infection. Cercarial antigen proved to give the highest sensitivity (75%) of the intradermal antigens. At this laboratory, sensitivity of all intradermal tests was considerably less than that obtained with the serological procedures. Sensitivity of the complement fixation test was 97% with adult antigen and 96% with cercarial antigen. Comparable results were obtained in the cercarial slide flocculation (98%) and the cercarial agglutination (98%) tests. However, a relatively large number (21%) of weak reactions were obtained in the agglutination test. The circumoval precipitin procedure showed a sensitivity of 88%.

All schistosome infections in the group of 355 patients, on whom all tests were performed, could have been detected serologically. A combination of either complement fixation test with the slide flocculation or agglutination test would have sufficed. In a like manner a combination of the slide flocculation procedure and the agglutination test would have detected all of the infections. The complement fixation tests and the slide flocculation test showed the greatest sensitivity.


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