1921
Volume 9, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

Summary

The reaction of cercarial antigen-cholesterol-lecithin complex with schistosome antibody provides a simple sensitive slide flocculation test for schistosome infections.

Capacity of the antigen emulsion to react with homologous antibody was greatly increased by removing the antigen-cholesterol-lecithin complex from the salt solution in which it was prepared and resuspending the complex in fresh salt solution.

The cercarial antigen used in the test also reacted with sera from patients with and infections.

While specificity of the test was excellent in other helminthic diseases, cross-reactions with the antigen and anti-sera did occur. This finding is consistent with those obtained from other tests using cercarial antigens.

The excellent sensitivity (98%) and simplicity of the procedure make the test ideally suited for field and survey purposes.

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/content/journals/10.4269/ajtmh.1960.9.299
1960-05-01
2017-11-21
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