1921
Volume 7, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

Summary

  • 1.  A pyrimethamine-resistant line of at least 640 times more resistant than the parent strain was developed in vitro.
  • 2.  The resistant nature of this line was retained for at least 3 months when the parasite was grown in the absence of pyrimethamine.
  • 3.  A pyrimethamine-requiring line of could not be developed.
  • 4.  The drug-resistant nature of this line of was not demonstrable in vivo.

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/content/journals/10.4269/ajtmh.1958.7.400
1958-07-01
2017-09-20
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