Volume 5, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


“No man can answer for his courage who has never been in danger.” LaRoche

The immunization of man against poliomyelitis with preparations of living attenuated virus has been practiced by myself and my associates for the past five and one-half years (Koprowski , 1952). All the results of the study cannot even be summarized in this lecture and, while I shall review some past events, I intend to concentrate on taking an inventory of the present.

. Three attenuated strains of virus have been used for the immunization of human subjects: two, the TN strain (Koprowski , 1952) and MEF strain (Roca-Garcia , 1952; Roca-Garcia and Jervis, 1955) represent Type II, and one, the SM strain (Koprowski , 1954a), represents Type I. The TN strain is a rodent-adapted virus.


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