1921
Volume 5, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

Summary

Guinea pigs inoculated with an aqueous suspension of killed developed dye test antibody but not complement fixing antibody. When an adjuvant was combined with the antigen both antibodies developed and considerable immunity resulted. The antigen was apparently associated with the whole rather than its extracts, even though the latter actively fixed complement. Whereas convalescent animals were able to resist an intracerebral inoculation of , the vaccinated animals were immune only to intradermal and intraperitoneal inoculation. It has been shown that are disseminated through the guinea pig even in the presence of very high levels of complement fixing antibody.

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/content/journals/10.4269/ajtmh.1956.5.197
1956-03-01
2017-11-21
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