1921
Volume 4, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

Summary

antivenin produced in Yugoslavia proved effective in protecting 20-gram white mice from lethal doses of venoms of and . In all potency tests intraperitoneal injections of venom were followed in 30 minutes by intraperitoneal injections of antivenin. Test animals were observed for a 24 hour period, after which time results were recorded. Death and survival were regarded as endpoints. Amounts of venom were expressed as portions of the contents of one venom gland. One-fourth the contents of one venom gland constituted the minimum certain lethal dose of venom for white mice. Complete protection against effects of two certain lethal doses of venom was afforded by amounts of antivenin as low as 0.1 cc. of a 1:1 dilution.

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/content/journals/10.4269/ajtmh.1955.4.762
1955-07-01
2017-11-24
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