Volume 3, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



An improved antigen for the complement-fixation test has been prepared by extracting desiccated adult schistosomes with anhydrous ether in the cold (-15 to -18°C.) prior to final extraction with buffered salt solution. Preliminary extraction with ether markedly reduced a tendency of the antigen to react with syphilitic serum without appreciably altering its capacity to fix complement specifically with serum from schistosome-infected individuals.

Sera from persons infected with or could not be differentiated on the basis of their capacity to react with antigens from the homologous and heterologous parasites.

The complement-fixation test is discussed from the point of view of its value in the diagnosis of schistosomiasis.


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