1921
Volume 3, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

This report describes an infection by West Nile virus in a technician who was working with the virus in the laboratory. Evidence favors the view that the infection was acquired in the laboratory. We have found no record of a similar case in the literature.

The West Nile virus was first isolated in 1937 from the blood of a febrile woman in the West Nile province of Uganda (Smithburn , 1940). It was again isolated in 1950 in an Egyptian village north of Cairo (Melnick , 1951). The virus when inoculated intracerebrally into Swiss mice produces an encephalitis and is highly fatal.

Southam and Moore (1952) in a study of the effect of the virus on neoplasms, experimentally infected 68 humans with a strain of West Nile virus (Egypt 101). Four patients developed definite signs of diffuse encephalitis and two patients showed transient signs of encephalitis.

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