Volume 1, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


Summary and Conclusions

Liver tissue was taken from 14 patients after massive sporozoite inoculations with a Panama strain of . The tissue was fixed in Carnoy's fluid, serially sectioned, and stained with a colophonium-Giemsa method.

Exo-erythrocytic parasites were found in the material derived from the patient receiving the heaviest inoculations. This patient had been inoculated on four successive days with a total of 8,516 mosquito bites and 1,403 salivary glands intravenously. The mosquitoes used averaged 86.8 per cent infected. Biopsy was done at laparotomy three to six days after inoculation. A total of about 125 parasites was found. The characteristics of these parasites indicate that they are part of the exo-erythrocytic phase of malaria. They are similar to those found by Shortt and his associates for this species of malaria.


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