1921
Volume 1, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

Summary

A series of compounds was tested for antimalarial activity against the erythrocytic forms of . Chloroquine, quinacrine, quinine, and the naphthoquinone, SN 12,320, were active at concentrations approximating those found in the blood of adequately treated chicks. Pamaquine was relatively inactive , but when administered to chickens gave rise to active metabolic intermediates. Sulfadiazine, metachloridine, chlorguanide, and two of its metabolic intermediates from monkeys, a number of 2,4-diaminopyrimidines, and a 2,4-diaminopterin were relatively inactive .

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/content/journals/10.4269/ajtmh.1952.1.132
1952-01-01
2017-09-21
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