Volume s1-31, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


The role of rat fleas in the transmission of murine typhus has been established by many investigators (1, 2, 3, 4, 5). Nevertheless, there are references in the literature which state that the urine of typhus-infected rats may be infectious (6, 7). In order to evaluate the possibility of transmission of typhus among rats in the absence of ectoparasites, transmission was attempted by urine and other excreta of infected rats and by fighting and cannibalism among infected and nonimmune rats.

MATERIALS AND METHODS . The Wilmington strain of murine typhus rickettsias was grown in the yolk sacs of fertile eggs (8). Roof rats, subspp., were infected by intraperitoneal inoculation of 0.5 cc. amounts of a 10-3 dilution of infectious yolk sac.

. The test was a modified Kolmer procedure described in detail elsewhere (9). Two units of soluble type antigen prepared from infected yolk sac were used (10).


Article metrics loading...

The graphs shown below represent data from March 2017
Loading full text...

Full text loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error