1921
Volume s1-30, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

Summary

Chloramphenicol was effective against amebae . Higher concentrations were required in the presence of coagulated whole egg than in egg yolk infusion. It exerted only transient suppressive action against amebic colitis in dogs but was effective against cecal infections in rats.

Although penicillin G was not amebacidal , when given orally it exerted some therapeutic effect in dogs and was highly effective in rats. Limited observations pointed to a similar discrepancy between action and therapeutic action in rats by streptomycin.

Bacitracin, subtilin and methylated subtilin did not exert encouraging antiamebic action , and bacitracin did not eradicate infections in dogs.

In vitro and experimental chemotherapeutic data are presented for carbarsone, acetarsone, diiodo-oxyquinoline, chiniofon, Vioform and emetine hydrochloride.

Phthalyl sulfacetimide was ineffective in rats and dogs.

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/content/journals/10.4269/ajtmh.1950.s1-30.203
1950-03-01
2017-11-18
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