Volume s1-29, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



  • 1)  “Mel B,” a new trivalent arsenical has been applied to the treatment of 50 cases of human second stage Sleeping Sickness, of which 20 cases presented trypanosomes in the CSF.
  • 2)  The cases have been controlled up to 7 months after the treatment.
  • 3)  The treatment had no untoward effect.
  • 4)  The trypanosomes disappeared in all cases without reoccurrence from lymph glands and blood, 24 hours after the first injection.
  • 5)  “Mel B” penetrates into the CSF and exerts a strong parasiticidal effect on the trypanosomes in the central nervous system.
  • 6)  A single series of 3–4 daily injections of “Mel B”, a treatment of 3–4 days duration, may restore the pathological CSF changes of advanced meningoencephalitis Sleeping Sickness cases to normal co-incident with clinical recovery.


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