1921
Volume s1-28, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

Summary

  • 1.  Three hundred and sixteen neotropical rodents, belonging to twenty different species, were tested against several strains of yellow fever virus.
  • 2.  and were found to be resistant to all strains of virus used. None circulated virus and, in general, the immunity response was poor.
  • 3.  Among the rodents belonging to the genera of and only a small percentage circulated traces of virus.
  • 4.  Of the three species of tested, one, , was found to be resistant to the virus. Individuals of circulated virus, in traces, after the inoculation of the Asibi strain but were resistant to two jungle strains (J.Z. and O.C.). However, rodents belonging to the species circulated virus when infected with any one of these three strains. In general circulating virus was present only in small amounts and persisted for only 1 or 2 days in the blood stream. However, occasional individuals circulated virus for longer periods.
  • 5.  Of the three species of tested, one () circulated more virus than the other two ( and ), both of which showed only traces of virus in the blood stream after inoculation.
  • 6.  was found to circulate virus after inoculation with the Asibi and the J. Z. strains, but not after inoculation with the O. C. strain. However, all the animals inoculated with the O. C. strain developed antibodies.
  • 7.  was the only species tested of which all the surviving animals circulated virus and developed neutralizing antibodies.
  • 8.  Of eight species tested against the French neurotropic strain only one, , was found to be susceptible.

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/content/journals/10.4269/ajtmh.1948.s1-28.231
1948-03-01
2017-09-20
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