Volume s1-27, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


Summary and Conclusions

The following points are based upon microfilarial counts of the blood of two patients parasitized with .

  • 1.  Microfilariae were present at all hours of the day and night regardless of whether or not the parasitized individuals were awake or asleep.
  • 2.  In these two cases peak counts over 26 hour periods were diurnal, the peaks occurring between noon and 8:00 p.m.
  • 3.  Conversely, the lowest densities were nocturnal, occurring between midnight and 8:00 a.m.
  • 4.  The ratio of the mean high and low daily counts in both patients was low, being 3.4 in the case of patient A and 2.3 in the case of patient B.
  • 5.  In patient A the count over a seven and one-half month period showed some increase in numbers of microfilarise in spite of drug therapy with stibanose.
  • 6.  In patient B the peak density occurred 11 months after microfilariae were first demonstrated in the patient's blood. Three months and a half later the count showed a decrease, although the patient received no therapy.
  • 7.  It is suggested that the term “diurnal periodicity” might be found to be more appropriate than the terms “non-periodic” or “aperiodic” which appear widely in the literature.


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