Volume s1-26, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


The antiseptic action of heteropolar cationic chemicals, or synthetic cationic detergents, against cysts of and against other micro-organisms, their relatively low acute oral toxicity, and their relative freedom from inactivation by high concentations of organic nitrogenous materials and alkalinity have suggested their use for the emergency sterilization of drinking water.

Two objections may be raised to this suggestion, however: (1) Antiseptic action of these chemicals might conceivably be reversed within the gastrointestinal tract; and (2) The slight taste and unknown risk of chronic toxicity would make it desirable to inactivate or remove excess chemical after antiseptic action has taken place.

I. FAILURE OF ANTISEPTIC ACTION TO BE REVERSED WITHIN THE INTESTINAL TRACT A heavy growth of was prepared on agar slants and divided into three portions which were made up into heavily turbid suspensions in sterile water and in 1:10,000 and 1:20,000 dilutions of Zephiran.


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