Volume s1-26, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



To determine the spatial distribution of murine typhus fever in San Antonio in 1944 and 1945 rats were collected throughout the city and tested for the presence of complement fixing antibodies for typhus. The human cases were investigated to determine the most probable source of infection. The city was divided into 6 arbitrary districts according to the characteristics of the inhabitants and amount of typhus.

Rats positive for typhus fever have been found in all districts but the good residential areas have low percentages of positives. The fairly good residential areas and the business districts have about 40 per cent of rats positive. The very poor slum district has about 60 per cent of the rats positive.

Human cases originated in all districts and showed a general but not detailed correlation with the percentages of positive rats. Apparently human infections depend upon a local concentration of positive rats rather than a uniform distribution of infected rats in an area.


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