1921
Volume s1-26, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

Summary

Attempts to interpose various marsupials and primates in laboratory cycles of yellow fever, using the mosquito as vector, are described. Of 11 attempts to infect haemagogus on the brown masked opossum () only one was successful, though 11 of 13 animals bitten by infected haemagogus showed circulating virus. One of 4 woolly opossums () showed circulating virus after being bitten by infected haemagogus. These two species are considered to be the most susceptible of Colombian marsupials, and it thus seems doubtful whether any of the local marsupials can play an important rôle in haemagogus cycles in nature.

The maintenance of cycles with haemagogus mosquitoes and various primates was relatively easy, and constant mosquito-mammal passages were maintained for a year (14 cycles) using saimiri and douroucouli monkeys and the marmoset . Attempts to infect the widow monkey () gave irregular results, and the local capuchin () in 4 instances failed to circulate enough virus to infect haemagogus mosquitoes. It thus seems likely that all monkeys are not equally important in the maintenance of virus cycles in nature.

Since the various species of mammals and mosquitoes and the various strains of virus show differences in behavior from place to place, it is considered important that transmission experiments be made with local materials in order to evaluate possible local transmissions mechanisms.

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/content/journals/10.4269/ajtmh.1946.s1-26.437
1946-07-01
2017-09-24
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