Volume s1-25, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


This investigation was inaugurated by the Health Service of the Czechoslovak Army eight years ago, for the purpose of producing a reliable combined vaccine against cholera and dysentery, which might be used in the eventuality that troops would be stationed in areas where these diseases are prevalent. Due to events preceding the present holocaust the experiments were necessarily interrupted and reopened during recent years in the United States.

A vaccine was sought which would protect against infections with and Y, the latter being chosen because of its ability to confer partial immunity against the most common Shigella strains, namely V, W and Z.

In order to determine which type of vaccine would confer maximum immunity, alcohol and heat killed organisms, and formolized and phenolized bacillary suspensions were tested. Organisms extracted with trichloracetic acid, formamate and diethylene glycol were utilized.


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  • Received : 28 Nov 1944
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