Volume s1-25, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


In 1919 Arkwright and Bacot and Duncan (1) removed 150 lice () from a typhus infected monkey (Macacus rhesus) just before death, which were inoculated subcutaneously and intramuscularly to another monkey of the same species. After an incubation period of 7 days this animal developed a febrile disease.

Dissection of the lice nourished on the infected monkeys indicated from 4–16% with rickettsiae in the digestive tract. In 1922 Atkin published the results of experiments made with Bacot in 1920 and 1921 at the Lister Institute in London, using a Polish and Irish virus (2). In this important work the authors demonstrated that the infected lice could not transmit infection by biting; a few experiments of experimental infection of on macaca monkeys are also reported.

Atkin and Bacot first took the intestinal tract of 36 Pedicinus from a on the 12th day of typhus, emulsified in normal saline, inoculating into the thigh of a macacus of the same species.


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  • Received : 18 Jul 1944
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