Volume s1-23, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


Originally we were accustomed to think of deficiency diseases as caused by the lack of specific vitamins. Thus, pellagra was caused by the deficiency of nicotinic acid; scurvy by the deficiency of ascorbic acid; and beriberi by the deficiency of thiamine. This conception was at least partly owing to experimental work on animals fed synthetic diets supposed to be deficient in single vitamins. But so far as humans are concerned, deficiency diseases arise from the use of more or less definite diets which are monotonous and usually can be easily shown to be lacking in several vitamins.

The complete clinical picture of pellagra, as we have learned largely from the work of Spies and his collaborators, although chiefly due to the deficiency of nicotinic acid, is modified by the additional deficiencies of thiamin, riboflavin, and almost certainly other vitamins of the B complex.


Article metrics loading...

The graphs shown below represent data from March 2017
Loading full text...

Full text loading...

  • Received : 11 May 1942
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error