Volume s1-22, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


It is generally recognized that in addition to the corpuscle maturing factor (E.M.F.) the Cohn fraction, which in various stages of purification forms the basis of all commercial liver extracts, also contains a factor which restores the ability of the intestine to absorb fats and other foods; an ability which is lost in sprue and which is responsible for most of its symptomatology (1). It is highly desirable to identify this factor.

In order to obtain experimental evidence concerning this latter factor it was determined to feed rats a diet adequate except for thiamine and the B complex but with the addition of the Cohn fraction of liver extract, and subsequently adding synthetic vitamins of the B complex as they were required to ensure growth. Any of these vitamins that were not required would presumably be present in the liver extract.

EXPERIMENT The diet used was as follows:

Casein, vitamin free 360 grams


Article metrics loading...

The graphs shown below represent data from March 2017
Loading full text...

Full text loading...

  • Received : 11 May 1942
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error