Volume s1-22, Issue 4_Suppl
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



Transmission experiments were undertaken in which wild sandflies, , were fed on rhesus monkeys. The sandflies were caught in the verruga zone, brought to Lima, placed in feeding-cages and applied to the bellies of the monkeys. The technique permits voluntary and natural feeding of the sandflies.

In one series, five out of eight monkeys became infected with . No skin lesions were produced. Infection was demonstrated by blood cultures, subsequent tests of such cultures in monkeys, and in two instances by immunity tests. While other mechanisms of transmission are theoretically possible, the conclusion is believed warranted that in these experiments transmission occurred by the bites of the sandflies.

Several species of South American monkeys were infected by inoculation of cultures. Nodules were produced from which was recovered in culture, though blood cultures failed.

The infection-rate of wild sandflies is discussed.


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