Volume s1-19, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



  • 1.  A generalized infection in a dog by a fungus proven to be identical with of Darling in all of its phases in both the tissues of its host, and in cultures is reported.
  • 2.  The fungus was cultivated and found to fulfil all of Koch's postulates.
  • 3.  This is the first report of Histoplasmosis occurring in any natural host other than man.
  • 4.  The disease was also transmitted to dogs and puppies by feeding them cultures of the fungus.
  • 5.  The infected dog might possibly transmit the infectious agent to man in infected excreta and secretions, or it might be possible that the flea or the tick acts as a transmitting agent.
  • 6.  Histoplasmosis is probably more common than is indicated by the medical literature.
  • 7.  In obscure cases of splenomegaly and lymphadenopathy, should be searched for in blood films, biopsies of lymph nodes, and in cultures of blood and lymph nodes.


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  • Received : 19 Sep 1939

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