Volume s1-16, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


Summary and Conclusions

A complement-fixation test for Chagas' disease, in which an artificial culture antigen is used, is described.

The antigen used in this test can be readily made from cultures of grown on a medium prepared essentially according to the method of Bonacci. Such antigen represents a distinct improvement over older types prepared from tissues of artificially infected animals.

The ease with which the antigen described herein can be prepared should make the complement-fixation test a more usable and valuable agent in the diagnosis of Chagas' disease and the identification of carriers.

No cross reactions occur with Wassermann-positive sera.

Sufficient work has not as yet been done to determine whether or not cross reaction will occur with sera from other types of trypanosomiasis.


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  • Received : 23 Apr 1936
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