Volume s1-11, Issue 2
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


Recent studies on the filtrability of yellow fever virus have brought out, in addition to other interesting data, the following facts.

  • 1.  Yellow fever mosquito-virus, in the absence of serum, is frequently inactivated by exposures of one or two hours, at about 25°C. to normal saline solution, distilled water, Locke's solution, Ringer's solution, and hormone broth; hence the apparent non-filtrability of the mosquito-virus in certain instances. Even blood-virus loses its infectivity in a short time if dilution is carried much beyond 10 per cent (1).
  • 2.  If a sufficient quantity (10 per cent or more) of normal monkey serum be added to saline or distilled water suspensions of mosquito-virus, the virus survives for longer intervals and passes “V,” “N,” and “W” Berkefeld filters readily (2, 1). The virus has, however, been demonstrated in a Berkefeld ifitrate in distified water in the absence of serum (1).


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