1921
Volume s1-6, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
USD

Abstract

Summary and Conclusions

  • 1.  Thirteen soldiers were treated with tetrachlorethylene in doses of 0.5 and 1.5 cc. and thirteen with a 2 to 1 combination of tetrachlorethylene and oil of chenopodium in doses of 1.5 and 2.4 cc. Efficiency rates of such dosages were calculated for species and sex on the basis of per cent removed by first treatment as tested by the administration of 3 cc. of oil of chenopodium.
  • 2.  Comparative results presented for tetrachlorethylene and carbon tetrachloride given in equal doses and under similar conditions show that carbon tetrachloride alone or in combination with oil of chenopodium is more efficient for than is tetrachlorethylene and that in combination with oil of chenopodium, carbon tetrachloride is more efficient than is tetrachlorethylene for . When given alone such superiority of carbon tetrachloride for is not apparent but the infestation of the cases studied was very low: this result should be checked against work done in areas of heavy infestation.
  • 3.  Tetrachlorethylene is definitely more effective against than against and is probably slightly more effective against females than against males of the same species. The decreasing order of resistance to a 2 to 1 combination of tetrachlorethylene and oil of chenopodium was found to be the same as that for a 2 to 1 combination of carbon tetrachloride and oil of chenopodium, viz.

    1. Female
    2. Male
    3. Male
    4. Female
  • 4.  From the present study it would appear that tetrachlorethylene offers no advantages over carbon tetrachloride in the treatment of hookworm disease in Paraguay, where the infestation is largely (93 per cent) . Further tests for toxicity and anthelmintic efficiency should be made in areas of heavy infestation to determine whether tetrachlorethylene is superior to carbon tetrachloride for use in such areas.

Loading

Article metrics loading...

/content/journals/10.4269/ajtmh.1926.s1-6.451
1926-11-01
2017-11-23
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.1926.s1-6.451
Loading

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error