Volume s1-6, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


The earliest statement in the literature that we can find relative to the occurrence of HCl in the stomach secretions in pellagra, is that of Angostoni in 1893 (1) quoted by H. F. Harris (9): “The study of the chemistry of the stomach of pellagrins shows a notable degree of and , with catarrh of the mucosa of the stomach and weakness of its and its . While in some instances the . The average was distinctly . Likewise varied from none at all to an amount, in some instances ” Harris himself says, in discussion, “There is a general agreement among the writers that there is as a rule, absence or great diminution in hydrochloric acid.” Nesbit, (11) at the National Conference for Pellagra (1909) reported analyses of the stomach contents of ten cases.


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