image of Case Report: Malignant Transformation of Noma: Repair by Forearm Flap
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


Noma is a progressive infectious disease manifested by a necrotic ulcer of the mouth and face. It usually occurs in poor, malnourished children, with about 30,000–140,000 cases each year and a low survival rate. The exact cause of noma remains unclear, but bacterial infection has been postulated to be a major cause of this disease. Antibiotics and improved nutrition could help inhibit the progression of noma, but most patients still require oral surgery because of the bacterial infection–induced tissue damage. In this study, we report an unusual case of a noma patient whose facial lesion developed a malignancy. The necrotic tissue and infectious area were surgically resected, and a forearm flap was used to repair the patient’s facial defect. This case aimed at increasing people’s awareness of tropical diseases such as noma.


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  • Received : 05 Dec 2019
  • Accepted : 06 Jul 2020
  • Published online : 10 Aug 2020
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