image of Case Report: Two Cases of Acute Q Fever from the Same Family Who Returned from Malawi to Japan
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


In July 2018, acute Q fever (AQF) was diagnosed in two Japanese individuals from the same family. They returned to Japan from Malawi, where the epidemiology of AQF is unknown. A child presented to the hospital with high-grade fever without any symptoms, and a mother presented with fever and dry cough. Paired serum antiphase Ⅱ IgM and IgG significantly elevated in the convalescent phase in both cases. gene () was detected from the mother’s blood sample. They had no reported direct animal contact, but the onset of symptoms coincided with the dry season in Malawi, which may have facilitated environmental dispersal. These cases may serve as an alert for high-risk people to possible AQF spread and underdiagnosis in Malawi.


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  • Received : 23 Jul 2019
  • Accepted : 15 Sep 2019
  • Published online : 28 Oct 2019
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