Volume 101, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



Recent data show that the gut microbiome plays a role in determining the clinical outcome of infection. We report the case of a patient who developed recurrent acute amebic colitis (second episode of acute colitis) after colonoscopy. Genotyping of revealed that she developed a second episode of acute amebic colitis with the same genotype as that of the first episode, indicating chronic infection had persisted asymptomatically for > 10 months between the first and second episodes. Analysis of the gut microbiome, in addition to the clinical findings, suggested that dysbiosis at colonoscopy induced the change in the clinical form of infection from asymptomatic chronic infection to symptomatic colitis.

[open-access] This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


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  • Received : 23 May 2019
  • Accepted : 20 Aug 2019
  • Published online : 07 Oct 2019

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