1921
Volume 101, Issue 3
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

Abstract.

Mass deworming of school-aged children with anthelmintics has been recognized as an effective approach for reducing the burden of soil-transmitted helminth (STH) infections. However, the consequences of this intervention on nontargeted parasite populations sharing the same gastrointestinal niche are unclear. We conducted a cross-sectional survey among three primary schools in Sululta town, Ethiopia, to examine the association between students’ histories of deworming treatment in the past 6 months and the prevalence of cestode and protozoan infections. An interviewer-led questionnaire administered to parents provided information on sociodemographic factors, and deworming status was ascertained from school records. Stool samples were collected from 525 children for microscopic examination. The independent associations of “” (positive either for or spp. eggs) and “ (positive either for or ) with history of deworming were examined using logistic regression. Overall, 25.9% of children were infected with at least one intestinal parasite of which was the most common. In multivariate analyses, deworming in the past 6 months was positively associated with increased odds of both “” and “” infections; the latter reached statistical significance (AOR = 1.83, 95% CI: 0.69–4.86, = 0.220, AOR = 3.82, 95% CI: 1.17–12.73, = 0.029, respectively). If this observed association is causal, a greater understanding of interspecies interactions within the gastrointestinal niche may elucidate possible consequences of mass deworming treatments against STHs on coexisting nontargeted parasites.

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Supplemental tables

  • Received : 15 Apr 2019
  • Accepted : 09 Jun 2019
  • Published online : 22 Jul 2019

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