image of Clock Gene Timeless in the Chagas Disease Vector Triatoma infestans (Hemiptera: Reduviidae)
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645


To contribute to a better understanding of the molecular basis of the circadian biological rhythms in Chagas disease vectors, in this work we identified functional domains in the sequences of the clock protein TIMELESS (TIM) in and analyzed the expression of the () gene at the mRNA level in . The gene expression in nervous tissue of adult revealed clear oscillations in the abundance of the transcript in both sexes in the group maintained under photoperiod with a daily canonical rhythm, showing a significant increase in expression at sunset. As expected, in the group maintained in constant light, no daily increase was detected in the transcript level.


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  • Received : 27 Feb 2019
  • Accepted : 05 Sep 2019
  • Published online : 07 Oct 2019
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