1921
Volume 101, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

Splenic infarction caused by malaria can be fatal, but its incidence and clinical presentation are not well-known. Thus, we investigated the prevalence and characteristics of splenic complications in patients with vivax malaria from 2005 to 2017 in a university hospital. Among 273 patients who were diagnosed with infection by blood smear, 92 underwent abdominal computed tomography or ultrasonography. Twelve patients had splenic infarction. All patients with splenic infarction recovered after treatment with antimalarial drugs, without surgery and intervention. Although anemia and prolonged fever may be risk factors for splenic infarction, the incidence of these events was insufficient for a detailed analysis.

Loading

Article metrics loading...

The graphs shown below represent data from March 2017
/content/journals/10.4269/ajtmh.19-0101
2019-08-19
2020-09-26
Loading full text...

Full text loading...

/deliver/fulltext/14761645/101/4/tpmd190101.html?itemId=/content/journals/10.4269/ajtmh.19-0101&mimeType=html&fmt=ahah

References

  1. Masters BR, 2016. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, Eighth Edition (2015) Eds: John E. Bennett, Raphael Dolin, Martin J. Blaser. ISBN: 13-978-1-4557-4801-3, Elsevier Saunders. Graefes Arch Clin Exp Ophthalmol 254: 22852287.
    [Google Scholar]
  2. Trampuz A, Jereb M, Muzlovic I, Prabhu RM, 2003. Clinical review: severe malaria. Crit Care 7: 315.
    [Google Scholar]
  3. Anstey NM, Douglas NM, Poespoprodjo JR, Price RN, 2012. Plasmodium vivax: clinical spectrum, risk factors and pathogenesis. Adv Parasitol 80: 151201.
    [Google Scholar]
  4. Hwang JH, Lee CS, 2014. Malaria-induced splenic infarction. Am J Trop Med Hyg 91: 10941100.
    [Google Scholar]
  5. Im JH, Kwon HY, Baek J, Park SW, Durey A, Lee KH, Chung MH, Lee JS, 2017. Severe Plasmodium vivax infection in Korea. Malar J 16: 51.
    [Google Scholar]
  6. Kim A, Park YK, Lee JS, Chung MH, Kim ES, 2007. A case of symptomatic splenic infarction in vivax malaria. Korean J Parasitol 45: 5558.
    [Google Scholar]
  7. Goerg C, Schwerk WB, 1990. Splenic infarction: sonographic patterns, diagnosis, follow-up, and complications. Radiology 174: 803807.
    [Google Scholar]
  8. Gupta BK, Sharma K, Nayak KC, Agrawal TD, Binani A, Purohit VP, Kochar DK, 2010. A case series of splenic infarction during acute malaria in northwest Rajasthan, India. Trans R Soc Trop Med Hyg 104: 8183.
    [Google Scholar]
  9. Aggarwal HK, Jain D, Kaverappa V, Jain P, Kumar A, Yadav S, 2013. Multiple splenic infarcts in acute Plasmodium vivax malaria: a rare case report. Asian Pac J Trop Med 6: 416418.
    [Google Scholar]
  10. Bonnard P, Guiard-Schmid J-B, Develoux M, Rozenbaum W, Pialoux G, 2005. Splenic infarction during acute malaria. Trans R Soc Trop Med Hyg 99: 8286.
    [Google Scholar]
  11. Vogetseder A, Ospelt C, Reindl M, Schober M, Schmutzhard E, 2004. Time course of coagulation parameters, cytokines and adhesion molecules in Plasmodium falciparum malaria. Trop Med Int Health 9: 767773.
    [Google Scholar]
  12. Mohanty D, Ghosh K, Nandwani SK, Shetty S, Phillips C, Rizvi S, Parmar BD, 1997. Fibrinolysis, inhibitors of blood coagulation, and monocyte derived coagulant activity in acute malaria. Am J Hematol 54: 2329.
    [Google Scholar]
  13. Cabrales P, Zanini GM, Meays D, Frangos JA, Carvalho LJ, 2010. Murine cerebral malaria is associated with a vasospasm-like microcirculatory dysfunction, and survival upon rescue treatment is markedly increased by nimodipine. Am J Pathol 176: 13061315.
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.19-0101
Loading
/content/journals/10.4269/ajtmh.19-0101
Loading

Data & Media loading...

  • Received : 02 Feb 2019
  • Accepted : 19 Jul 2019
  • Published online : 19 Aug 2019
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error