1921
image of Serotype Distribution and Antimicrobial Resistance of Shigella Species in Bangui, Central African Republic, from 2002 to 2013
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

is a major cause of severe diarrhea in children less than the age of 5 years in sub-Saharan Africa. The aim of this study was to describe the (sub-)serotype distribution and antimicrobial susceptibility of serogroups from Centrafrican patients with diarrhea between 2002 and 2013. We collected 443 isolates in total. The most common serogroups were ( = 243, 54.9%), followed by ( = 90, 20.3%) and ( = 72, 16.3%). The high diversity of (sub-)serotypes of and may impede the development of an efficient vaccine. Rates of resistance were high for ampicillin, chloramphenicol, tetracycline, and cotrimoxazole but low for many other antimicrobials, confirming recommendations for the use of third-generation cephalosporins (only one organism resistant) and fluoroquinolones (no resistance). However, the detection of one extended-spectrum beta-lactamase–producing organism highlights the need for continued monitoring of antimicrobial drug susceptibility.

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/content/journals/10.4269/ajtmh.17-0917
2018-06-25
2018-07-16
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http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.17-0917
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  • Published online : 25 Jun 2018
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