1921
Volume 98 Number 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

The ongoing Zika pandemic has affected many countries that are common travel destinations. We assessed the willingness to receive a prophylactic Zika virus (ZIKV) vaccine, currently under development, among travelers to areas with reported autochthonous ZIKV transmission. We surveyed United States (U.S.) residents aged 18–44 years who had ever heard of ZIKV and planned to travel to Florida and/or Texas ( = 420) or a U.S. territory or foreign country ( = 415) in 2017, using a nationally representative internet panel. Travelers to Florida and/or Texas reported less concern about ZIKV infection than travelers to other destinations (27% versus 36%, = 0.01). Female sex, Hispanic ethnicity, discussing ZIKV with medical professionals, ZIKV risk perception, and self-efficacy for ZIKV prevention predicted concern about ZIKV infection in both groups. Travelers to Florida and/or Texas (43%) and other destinations (44%) were equally willing to receive a ZIKV vaccine. Hispanic ethnicity, discussing ZIKV with medical professionals, and concern about ZIKV infection predicted vaccine willingness in both groups. Likelihood of using existing ZIKV prevention methods, confidence in the U.S. government to prevent ZIKV spread, self-efficacy for ZIKV prevention, and knowledge about ZIKV symptoms further predicted vaccine willingness in travelers to other destinations. In multivariable analyses, only concern about ZIKV infection was associated with vaccine willingness in both groups (prevalence ratio [95% confidence interval]: Florida and/or Texas: 1.34 [1.06, 1.69]; other: 1.82 [1.44, 2.29]). Targeted communications can educate travelers, particularly travelers who are pregnant or may become pregnant, about ZIKV risk to generate ZIKV vaccine demand.

[open-access] This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Loading

Article metrics loading...

/content/journals/10.4269/ajtmh.17-0907
2018-06-08
2018-07-19
Loading full text...

Full text loading...

/deliver/fulltext/14761645/98/6/tpmd170907.html?itemId=/content/journals/10.4269/ajtmh.17-0907&mimeType=html&fmt=ahah

References

  1. Centers for Disease Control and Prevention, 2017. World Map of Areas with Risk of Zika. Available at: https://wwwnc.cdc.gov/travel/page/world-map-areas-with-zika. Accessed September 6, 2017.
  2. International Trade Administration, 2015. U.S. Citizen Traffic to Overseas Regions, Canada & Mexico. Available at: https://travel.trade.gov/view/m-2015-O-001/index.html. Accessed September 6, 2017.
  3. Duffy MR, 2009. Zika virus outbreak on Yap Island, Federated States of Micronesia. N Engl J Med 360: 25362543.
  4. França GVA, 2016. Congenital Zika virus syndrome in Brazil: a case series of the first 1501 livebirths with complete investigation. Lancet 388: 891897.
  5. Moore CA, 2017. Characterizing the pattern of anomalies in congenital Zika syndrome for pediatric clinicians. JAMA Pediatr 171: 288296.
  6. Garcez PP, Loiola EC, Madeiro da Costa R, Higa LM, Trindade P, Delvecchio R, Nascimento JM, Brindeiro R, Tanuri A, Rehen SK, , 2016. Zika virus impairs growth in human neurospheres and brain organoids. Science 352: 816818.
  7. dos Santos T, 2016. Zika virus and the Guillain–Barré syndrome—case series from seven countries. N Engl J Med 375: 15981601.
  8. Centers for Disease Control and Prevention, 2016. Case Counts in the US. Available at: https://www.cdc.gov/zika/reporting/2016-case-counts.html. Accessed March 9, 2018.
  9. Centers for Disease Control and Prevention, 2017. Zika Travel Information. Traveler’s Health Information. Available at: https://wwwnc.cdc.gov/travel/page/zika-travel-information?s_cid=Zika-OADC-Search_CONUS-English-002. Accessed September 20, 2017.
  10. Paules CI, Fauci AS, , 2017. Emerging and reemerging infectious diseases: the dichotomy between acute outbreaks and chronic endemicity. JAMA 317: 691692.
  11. Richner JM, 2017. Vaccine mediated protection against Zika virus-induced congenital disease. Cell 170: 273283.
  12. Shan C, 2017. A live-attenuated Zika virus vaccine candidate induces sterilizing immunity in mouse models. Nat Med 23: 763767.
  13. Abbink P, 2016. Protective efficacy of multiple vaccine platforms against Zika virus challenge in rhesus monkeys. Science 353: 11291132.
  14. Collins MH, Metz SW, , 2017. Progress and works in progress: update on flavivirus vaccine development. Clin Ther 39: 15191536.
  15. Larocca RA, 2016. Vaccine protection against Zika virus from Brazil. Nature 536: 474478.
  16. Barouch DH, Thomas SJ, Michael NL, , 2017. Prospects for a Zika virus vaccine. Immunity 46: 176182.
  17. GfK, 2017. GfK Knowledge Panel. Available at: http://www.gfk.com/en-us/products-a-z/us/knowledgepanel-united-states/. Accessed September 20, 2017.
  18. Squiers L, 2018. ZIKV prevention: United States travelers’ knowledge, risk perceptions, and behavioral intentions—a national survey. Am J Trop Med Hyg 98: 18371847.
  19. United States Census Bureau, 2015. American Community Survey: Data Tables and Tools. Available at: https://www.census.gov/acs/www/data/data-tables-and-tools/index.php. Accessed January 5, 2018.
  20. Centers for Disease Control and Prevention, 2017. Zika Travel Information. Available at: https://wwwnc.cdc.gov/travel/page/zika-travel-information. Accessed September 6, 2017.
  21. Angelidou A, Michael Z, Hotz A, Friedman K, Emani S, LaRovere K, Christou H, , 2017. Is there more to Zika? Complex cardiac disease in a case of congenital Zika syndrome. Neonatology 113: 177182.
  22. Satterfield-Nash A, 2017. Health and development at age 19–24 months of 19 children who were born with microcephaly and laboratory evidence of congenital Zika virus infection during the 2015 Zika virus outbreak—Brazil, 2017. MMWR Morb Mortal Wkly Rep 66: 13471351.
  23. Kapogiannis BG, Chakhtoura N, Hazra R, Spong CY, , 2017. Bridging knowledge gaps to understand how Zika virus exposure and infection affect child development. JAMA Pediatr 171: 478485.
  24. Boer H, Seydel ER, , 1996. Protection motivation theory. Conner M, Norman P, eds. Predicting Health Behaviour: Research and Practice with Social Cognition Models. Buckingham, United Kingdom: Open University Press, 95–120.
  25. Wong LP, Alias H, Aghamohammadi N, Sam IC, AbuBakar S, , 2017. Differences in perceived severity of Zika virus infection and dengue fever and its influence on mosquito control practices in Malaysia. J Community Health 42: 854864.
  26. Taha SA, Matheson K, Anisman H, , 2013. The 2009 H1N1 influenza pandemic: the role of threat, coping, and media trust on vaccination intentions in Canada. J Health Commun 18: 278290.
  27. Chapman GB, Coups EJ, , 2006. Emotions and preventive health behavior: worry, regret, and influenza vaccination. Health Psychol 25: 8290.
  28. Liao Q, Wong WS, Fielding R, , 2013. How do anticipated worry and regret predict seasonal influenza vaccination uptake among Chinese adults? Vaccine 31: 40844090.
  29. Bacaner N, Stauffer B, Boulware DR, Walker PF, , 2004. Travel medicine considerations for North American immgrants visiting friends and relatives. JAMA 291: 28562864.
  30. Neave PE, Behrens RH, Jones COH, , 2014. “You’re losing your Ghanaianess”: understanding malaria decision-making among Africans visiting friends and relatives in the UK. Malar J 13: 287.
  31. Wong L, Alias H, Hassan J, AbuBakar S, , 2017. Attitudes towards Zika screening and vaccination acceptability among pregnant women in Malaysia. Vaccine 35: 59125917.
  32. Ellingson MK, Bonk CM, Chamberlain AT, , 2017. A survey-based study of Zika virus communication preferences among pregnant women in Georgia, United States. BMC Pregnancy Childbirth 17: 19.
  33. Finer LB, Zolna MR, , 2016. Declines in unintended pregnancy in the United States, 2008–2011. N Engl J Med 374: 843852.
  34. Blakey SM, Abramowitz JS, , 2017. Psychological predictors of health anxiety in response to the Zika virus. J Clin Psychol Med Settings 24: 270278.
http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.17-0907
Loading
/content/journals/10.4269/ajtmh.17-0907
Loading

Data & Media loading...

Supplementary Data

Supplemental Appendix

  • Received : 21 Nov 2017
  • Accepted : 06 Feb 2018

Most Cited This Month

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error