Volume 99, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



St.Louis encephalitis virus (SLEV) is an emerging human pathogen flavivirus in Argentina. Recently, it has reemerged in the United States. We evaluated the role as amplifying host of six resident bird species and analyzed their capacity as host during the 2005 encephalitis outbreak of SLEV in Córdoba. Eared Dove, Picui Ground Dove, and House Sparrow were the three species with highest host competence index. At a city level, Eared Dove and Picui Ground Dove were the most important amplifying hosts during the 2005 SLEV human outbreak in Córdoba city. This finding highlighted important differences in the SLEV ecology between Argentina and the United States. Characterizing and evaluating the SLEV hosts contribute to our knowledge about its ecology and could help us to understand the causes that promote its emergence as a human pathogen in South America.


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  1. Reisen WK, , 2003. Epidemiology of St. Louis encephalitis virus. Adv Virus Res 61: 139183. [Google Scholar]
  2. Spinsanti L, 2003. St. Louis encephalitis in Argentina: the first case reported in the last seventeen years. Emerg Infect Dis 9: 271273. [Google Scholar]
  3. Rocco IM, 2005. St. Louis encephalitis virus: first isolation from a human in São Paulo State, Brazil. Rev Inst Med Trop São Paulo 47: 281285. [Google Scholar]
  4. Spinsanti LI, 2008. Human outbreak of St. Louis encephalitis detected in Argentina, 2005. J Clin Virol 42: 2733. [Google Scholar]
  5. López H, Neira J, Morales MA, Fabbri C, D’Agostino ML, Zitto T, , 2011. Encefalitis por virus San Luis en la Ciudad de Buenos Aires durante el brote de dengue 2009. Medicina (B Aires) 71: 247250. [Google Scholar]
  6. Fabbri CM, Morales MA, Luppo VC, CappatoBerger F, Balanitro B, Manrique M, Fierro F, Goenaga S, Enria DA, Levis SC, , 2011. Brote de encefalitis de San Luis en la Provincia de San Juan, Argentina. Rev Argent Microbiol 1: 89. [Google Scholar]
  7. Seijo A, 2011. Brote de encefalitis de San Luis en el área metropolitana Buenos Aires. Medicina (B Aires) 71: 211217. [Google Scholar]
  8. Mondini A, 2007. Saint Louis encephalitis virus, Brazil. Emerg Infect Dis 13: 176178. [Google Scholar]
  9. Terzian AC, Mondini A, Bronzoni RV, Drumond BP, Ferro BP, Cabrera EM, Figueiredo LT, Chiaravalloti-Neto F, Nogueira ML, , 2011. Detection of Saint Louis encephalitis virus in dengue-suspected cases during a dengue 3 outbreak. Vector Borne Zoonotic Dis 11: 291300. [Google Scholar]
  10. Rosa R, Costa EA, Marques RE, Oliveira TS, Furtini R, Bomfim MR, Teixeira MM, Paixão TA, Santos RL, , 2013. Isolation of Saint Louis encephalitis virus from a horse with neurological disease in Brazil. PLoS Negl Trop Dis 7: e2537. [Google Scholar]
  11. Venkat H, 2015. Concurrent outbreaks of St. Louis encephalitis virus and West Nile virus disease–Arizona, 2015. MMWR Morb Mortal Wkly Rep 64: 13491350. [Google Scholar]
  12. White GS, Symmes K, Sun P, Fang Y, Garcia S, Steiner C, Smith K, Reisen WK, Coffey LL, , 2016. Reemergence of St. Louis encephalitis virus, California, 2015. Emerg Infect Dis 22: 21852188. [Google Scholar]
  13. Díaz LA, Albrieu Llinás G, Vázquez A, Tenorio A, Contigiani MS, , 2012. Silentcirculation of St. Louis encephalitis virus prior to an encephalitis outbreak in Cordoba, Argentina (2005). PLoS Negl Trop Dis 6: e1489. [Google Scholar]
  14. Diaz LA, Flores FS, Beranek M, Rivarola ME, Almirón WR, Contigiani MS, , 2013. Transmission of endemic St. Louis encephalitis virus strains by local Culex quinquefasciatus populations in Cordoba, Argentina. Trans R Soc Trop Med Hyg 107: 332334. [Google Scholar]
  15. Monath TP, Sabattini MS, Pauli R, Daffner JF, Mitchell CJ, Bowen GS, Cropp CB, , 1985. Arbovirus investigations in Argentina, 1977–1980. IV Serological surveys and sentinel equine program. Am J Trop Med Hyg 34: 966975. [Google Scholar]
  16. Quaglia AI, Diaz LA, Argibay H, Contigiani MS, Saggese MD, , 2014. West Nile and St. Louis encephalitis viruses antibodies surveillance in captive and free-ranging birds of prey from Argentina. EcoHealth 11: 603609. [Google Scholar]
  17. Diaz LA, Quaglia AI, Konigheim BS, Boris AS, Aguilar JJ, Komar N, Contigiani MS, , 2016. Activity patterns of St. Louis encephalitis and West Nile viruses in free ranging birds during a human encephalitis outbreak in Argentina. PLoS One 11: e0161871. [Google Scholar]
  18. Nasci RS, Mitchell CJ, , 1996. Arbovirus titer variation in field-collected mosquitoes. J Am Mosq Control Assoc 12: 167171. [Google Scholar]
  19. Diaz LA, Occelli M, Almeida FL, Almirón WR, Contigiani MS, , 2008. Eared dove (Zenaida auriculata, Columbidae) as host for St. Louis encephalitis virus (Flaviviridae, Flavivirus). Vector Borne Zoonotic Dis 8: 277282. [Google Scholar]
  20. Komar N, Dohm DJ, Turell MJ, Spielman A, , 1999. Eastern equine encephalitis virus in birds: relative competence of European starlings (Sturnus vulgaris). Am J Trop Med Hyg 60: 387391. [Google Scholar]
  21. Mitchell CJ, Monath TP, Sabattini MS, , 1980. Transmission of St. Louis encephalitis virus from Argentina by mosquitoes of the Culex pipiens (Diptera: Culicidae) complex. J Med Entomol 17: 282287. [Google Scholar]
  22. Komar N, Panella NA, Langevin SA, Brault AC, Amador M, Edwards E, Owen JC, , 2005. Avian hosts for West Nile virus in St. Tammany Parish, Louisiana, 2002. Am J Trop Med Hyg 73: 10311037. [Google Scholar]
  23. Gregory RD, Gibbons DW, Donald PF, , 2004. Bird census and survey techniques. Sutherland WJ, Newton I, et Green RE, eds. Bird Ecology and Conservation. Oxford, United Kingdom: Oxford University Press, 17–56.
  24. Komar N, Langevin S, Hinten S, Nemeth N, Edwards E, Hettler D, Davis B, Bowen R, Bunning M, , 2003. Experimental infection of North American birds with the New York 1999 strain of West Nile virus. Emerg Infect Dis 9: 311322. [Google Scholar]
  25. Reisen WK, Fang Y, Martinez VM, , 2005. Avian host and mosquito (Diptera: Culicidae) vector competence determine the efficiency of West Nile and St. Louis encephalitis virus transmission. J Med Entomol 42: 367375. [Google Scholar]
  26. Kilpatrick AM, LaDeau SL, Marra PP, , 2007. The ecology and impact of West Nile virus in the Western Hemisphere. Auk 124: 11211136. [Google Scholar]
  27. Reisen WK, Hahn DC, , 2007. Comparison of immune responses of brown-headed cowbird and related blackbirds to west Nile and other mosquito-borne encephalitis viruses. J Wildl Dis 43: 439449. [Google Scholar]
  28. Diaz LA, Nemeth NM, Bowen RA, Almiron WR, Contigiani MS, , 2011. Comparison of argentinean Saint Louis encephalitis virus non-epidemic and epidemic strain infections in an avian model. PLoS Negl Trop Dis 5: e1177. [Google Scholar]
  29. Duggal NK, 2014. Evidence for co-evolution of West Nile virus and house sparrows in North America. PLoS Negl Trop Dis 8: e3262. [Google Scholar]
  30. Hoyos LE, Cingolani AM, Zak MR, Vaieretti MV, Gorla DE, Cabido MR, , 2013. Deforestation and precipitation patterns in the arid Chaco forests of central Argentina. Appl Veg Sci 16: 260271. [Google Scholar]
  31. Calamari NC, Dardanelli S, Canavelli SB, , 2011. Variaciones en la abundancia poblacional de palomas medianas a lo largo del tiempo. INTA EEA Paraná. Serie Extensión 64: 2328. [Google Scholar]
  32. Vergara Cid C, Estallo EL, Almirón WR, Contigiani MS, Spinsanti LI, , 2013. Landscape determinants of Saint Louis encephalitis human infections in Córdoba city, Argentina during 2010. Acta Trop 125: 303308. [Google Scholar]
  33. Batallán GP, Estallo EL, Flores FS, Sartor P, Contigiani MS, Almirón WR, , 2015. St. Louis Encephalitis virus mosquito vectors dynamics in three different environments in relation to remotely sensed environmental conditions. Acta Trop 146: 5359. [Google Scholar]
  34. Paull SH, Song S, McClure KM, Sackett LC, Kilpatrick AM, Johnson PT, , 2012. From superspreaders to disease hotspots: linking transmission across hosts and space. Front Ecol Environ 10: 7582. [Google Scholar]

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  • Received : 03 Nov 2017
  • Accepted : 26 Mar 2018
  • Published online : 14 May 2018

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