1921
Volume 98, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

Cutaneous Leishmaniasis (CL) is a public health concern caused by () and in Libya. Information on sandfly vectors, as well as their associated species, is of paramount importance because vector dispersion is one of the major factors responsible for pathogen dissemination. A number of 515 sandflies (275 males and 240 females) were collected during June–November 2012 using the Centers for Disease Control miniature light traps from Al Rabta, northwest of Libya. Two hundred and forty unfed females were identified; () ( = 97), ( = 27), ( = 32), () ( = 38), and ( = 46). These flies were screened for DNA using the polymerase chain reaction–restriction fragment length polymorphism analysis of the internal transcribed spacer 1 and sequencing. Two were found positive to DNA. This finding should be considered for any further vector surveillance and epidemiological studies of CL in endemic areas across Libya.

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References

  1. Aoun K, Bouratbine A, , 2014. Cutaneous leishmaniasis in North Africa: a review. Parasite 21: 14. [Google Scholar]
  2. Dokhan MR, Kenawy MA, Doha SA, El-Hosary SS, Shaibi T, Annajar BB, , 2016. Entomological studies of phlebotomine sand flies (Diptera: Psychodidae) in relation to cutaneous leishmaniasis transmission in Al Rabta, north west of Libya. Acta Trop 154: 95101. [Google Scholar]
  3. Ashford R, Chance M, Ebert F, Schnur L, Bushwereb A, Drebi S, , 1976. Cutaneous leishmaniasis in the Libyan Arab Republic: distribution of the disease and identity of the parasite. Ann Trop Med Parasitol 70: 401409. [Google Scholar]
  4. Aoun K, Bousslimi N, Haouas N, Babba H, El-Buni A, Bouratbine A, , 2006. First report of Leishmania (L.) killicki Rioux, Lanotte & Pratlong, 1986 in Libya. Parasite 13: 8788. [Google Scholar]
  5. Magill AJ, Grogl M, Gasser RA, Jr. Sun W, Oster CN, , 1993. Visceral infection caused by Leishmania tropica in veterans of Operation Desert Storm. N Engl J Med 328: 13831387. [Google Scholar]
  6. Shehata MG, Samy AM, Doha SA, Fahmy AR, , 2014. Natural and experimental evidence of viscerotropic infection caused by Leishmania tropica from North Sinai, Egypt. J Egypt Soc Parasitol 44: 425434. [Google Scholar]
  7. Amro A, Gashout A, Al-Dwibe H, Alam MZ, Annajar B, Hamarsheh O, Shubar H, Schönian G, , 2012. First molecular epidemiological study of cutaneous leishmaniasis in Libya. PLoS Negl Trop Dis 6: e1700. [Google Scholar]
  8. Belal US, Abdel-Hafeez EH, Naoi K, Norose K, , 2012. Cutaneous leishmaniasis in the Nalut district, Libyan Arab Jamahiriya: a clinico-epidemiologic study and Leishmania species identification. J Parasitol 98: 12511256. [Google Scholar]
  9. Jaouadi K, Depaquit J, Haouas N, Chaara D, Gorcii M, Chargui N, Dedet J-P, Pratlong F, Boubabous R, Babba H, , 2012. Twenty-four new human cases of cutaneous leishmaniasis due to Leishmania killicki in Metlaoui, southwestern Tunisia: probable role of Phlebotomus sergenti in the transmission. Acta Trop 122: 276283. [Google Scholar]
  10. Boubidi S, Benallal K, Boudrissa A, Bouiba L, Bouchareb B, Garni R, Bouratbine A, Ravel C, Dvorak V, Votypka J, , 2011. Phlebotomus sergenti (Parrot, 1917) identified as Leishmania killicki host in Ghardaia, south Algeria. Microbes Infect 13: 691696. [Google Scholar]
  11. Guilvard E, Rioux J-A, Gallego M, Pratlong F, Mahjour J, Martinez-Ortega E, Dereure J, Saddiki A, Martini A, , 1991. Leishmania tropica au Maroc. III—rôle vecteur de Phlebotomus sergenti: a propos de 89 isolats. Ann Parasitol Hum Comp 66: 9699. [Google Scholar]
  12. Shehata MG, Samy AM, Doha SA, Fahmy AR, Kaldas RM, Furman BD, Villinski JT, , 2009. First report of Leishmania tropica from a classical focus of L. major in North-Sinai, Egypt. Am J Trop Med Hyg 81: 213218. [Google Scholar]
  13. Croset H, Rioux J, Maistre M, Bayar N, , 1978. The phlebotomines of Tunisia (Diptera-Phlebotominae). A revision of the systematics, distribution and behaviour (author’s transl). Ann Parasitol Hum Comp 53: 711749. [Google Scholar]
  14. Schönian G, Nasereddin A, Dinse N, Schweynoch C, Schallig HD, Presber W, Jaffe CL, , 2003. PCR diagnosis and characterization of Leishmania in local and imported clinical samples. Diagn Microbiol Infect Dis 47: 349358. [Google Scholar]
  15. Altschul SF, Gish W, Miller W, Myers EW, Lipman DJ, , 1990. Basic local alignment search tool. J Mol Biol 215: 403410. [Google Scholar]
  16. Tamura K, Stecher G, Peterson D, Filipski A, Kumar S, , 2013. MEGA6: molecular evolutionary genetics analysis version 6.0. Mol Biol Evol 30: 27252729. [Google Scholar]
  17. Annajar BB, , 1999. Epidemiology of cutaneous leishmaniasis in Libya. PhD Thesis, Keele University, Newcastle, United Kingdom, 189.
  18. Samy AM, Annajar BB, Dokhan MR, Boussaa S, Peterson AT, , 2016. Coarse-resolution ecology of etiological agent, vector, and reservoirs of zoonotic cutaneous leishmaniasis in Libya. PLoS Negl Trop Dis 10: e0004381. [Google Scholar]
  19. Ashford R, Schnur L, Chance M, Samaan S, Ahmed H, , 1977. Cutaneous leishmaniasis in the Libyan Arab Republic: preliminary ecological findings. Ann Trop Med Parasitol 71: 265271. [Google Scholar]
  20. Jaouadi K, Bettaieb J, Bennour A, Salem S, Rjeibi MR, Chaabane S, Yazidi R, Khabouchi N, Gharbi A, Salah AB, , 2017. First report on natural infection of Phlebotomus sergenti with Leishmania tropica in a classical focus of Leishmania major in Tunisia. Am J Trop Med Hyg 97: 291294. [Google Scholar]
  21. Jacobson RL, , 2003. Leishmania tropica (Kinetoplastida: Trypanosomatidae)—a perplexing parasite. Folia Parasitol (Praha) 50: 241250. [Google Scholar]
  22. Echchakery M, Chicharro C, Boussaa S, Nieto J, Carrillo E, Sheila O, Moreno J, Boumezzough A, , 2017. Molecular detection of Leishmania infantum and Leishmania tropica in rodent species from endemic cutaneous leishmaniasis areas in Morocco. Parasit Vectors 10: 454. [Google Scholar]
  23. Jaouadi K, Haouas N, Chaara D, Gorcii M, Chargui N, Augot D, Pratlong F, Dedet J-P, Ettlijani S, Mezhoud H, , 2011. First detection of Leishmania killicki (Kinetoplastida, Trypanosomatidae) in Ctenodactylus gundi (Rodentia, Ctenodactylidae), a possible reservoir of human cutaneous leishmaniasis in Tunisia. Parasit Vectors 4: 159. [Google Scholar]
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  • Received : 18 Oct 2017
  • Accepted : 19 Jan 2018
  • Published online : 12 Mar 2018

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