Volume 99, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



We describe the case of a patient with severe fever with thrombocytopenia syndrome (SFTS) complicated by SFTS-associated encephalopathy who was successfully treated with 4-day plasma exchange followed by two-time convalescent plasma therapy. During plasma exchange, the plasma cytokines interferon-α and inducible protein-10 gradually decreased without change of plasma viral load. However, plasma viral load gradually decreased after convalescent plasma therapy. This case provides important insights for understanding the mechanisms of experimental therapy in severely affected SFTS patients.


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Supplemental files

  • Received : 01 Oct 2017
  • Accepted : 30 May 2018
  • Published online : 01 Oct 2018

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