1921
Volume 98, Issue 4
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

In 2004, there existed limited tuberculosis (TB) research capacity in the country of Georgia. In response, a collaborative research training program (RTP) supported by a National Institutes of Health Fogarty International Center Global Infectious Diseases grant was formed between a U.S. academic institution and the National Center for Tuberculosis and Lung Disease (NCTLD) and other institutions in Georgia. We sought to assess outcomes of this RTP. The TB RTP combined didactic and mentored research training for Georgian trainees. Long-term trainees were supported for a 2-year period and with posttrainee career development mentoring. Metrics used to measure program performance included publications, grants received, and career advancement. From 2004 to 2015, 20 trainees participated in the program with 15 (75%) authoring a total of 65 publications in PubMed-listed journals. The median number of publications per trainee was six (interquartile range 2–14). A total of 16 (80%) trainees remain working in the area of TB; nine were promoted to leadership positions and three to lead research units at Georgian institutions. Ten (50%) trainees were the principal investigator (PI) of a peer-reviewed external grant after Fogarty-supported training, and 40% served as research mentors. Annual TB-related research funding at the NCTLD increased from $5,000 in 2005 to ∼$1.5 million in 2017. A Georgian Fogarty trainee was either PI, site PI, or coinvestigator on > 90% of all research funding. We believe that the NIH Fogarty-funded TB research training grant has made critical contributions to increasing the TB-related research infrastructure and capacity in Georgia, particularly at the NCTLD.

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References

  1. Chkhartishvili N, Chokoshvili O, Abutidze A, Dvali N, Del Rio C, Tsertsvadze T, , 2017. Progress toward achieving the UNAIDS 90-90-90 goals in HIV care from diagnosis to durable viral suppression in the country of Georgia. AIDS Res Hum Retroviruses 33: 9991003. [Google Scholar]
  2. Zachariah R, Harries AD, Ishikawa N, Rieder HL, Bissell K, Laserson K, Massaquoi M, Van Herp M, Reid T, , 2009. Operational research in low-income countries: what, why, and how? Lancet Infect Dis 9: 711717. [Google Scholar]
  3. Abutidze A, Bolokadze N, Chkhartishvili N, Sharvadze L, Tsertsvadze T, , 2016. Incidence of tuberculosis among HIV/HCV co-infected patients receiving hepatitis C treatment with pegylated interferon and ribavirin in Georgia. Georgian Med News 252: 1015. [Google Scholar]
  4. Heimburger DC, Carothers CL, Blevins M, Warner TL, Vermund SH, , 2015. Impact of global health research training on scholarly productivity: the Fogarty International Clinical Research Scholars and Fellows Program. Am J Trop Med Hyg 93: 12011207. [Google Scholar]
  5. Zunt JR, 2016. The National Institutes of Health Fogarty International Center global health scholars and fellows program: collaborating across five consortia to strengthen research training. Am J Trop Med Hyg 95: 728734. [Google Scholar]
  6. Vermund SH, , 2017. The vital case for global health investments by the United States Government. Clin Infect Dis 64: 707710. [Google Scholar]
  7. Drain PK, Subbaraman R, Heimburger DC, , 2017. Preserving the Fogarty International Center—benefits for Americans and the World. N Engl J Med 377: 911. [Google Scholar]
  8. Mdivani N, 2008. High prevalence of multidrug-resistant tuberculosis in Georgia. Int J Infect Dis 12: 635644. [Google Scholar]
  9. Weinstock DM, Hahn O, Wittkamp M, Sepkowitz KA, Khechinashvili G, Blumberg HM, , 2001. Risk for tuberculosis infection among internally displaced persons in the Republic of Georgia. Int J Tuberc Lung Dis 5: 164169. [Google Scholar]
  10. Zachariah R, 2016. Building global capacity for conducting operational research using the SORT IT model: where and who? PLoS One 11: e0160837. [Google Scholar]
  11. Zachariah R, 2010. The published research paper: is it an important indicator of successful operational research at programme level? Trop Med Int Health 15: 12741277. [Google Scholar]
  12. Powell K, , 2016. Does it take too long to publish research? Nature 530: 148151. [Google Scholar]
  13. Lomtadze N, Aspindzelashvili R, Janjgava M, Mirtskhulava V, Wright A, Blumberg HM, Salakaia A, , 2009. Prevalence and risk factors for multidrug-resistant tuberculosis in the Republic of Georgia: a population-based study. Int J Tuberc Lung Dis 13: 6873. [Google Scholar]
  14. Gegia M, Kalandadze I, Kempker RR, Magee MJ, Blumberg HM, , 2012. Adjunctive surgery improves treatment outcomes among patients with multidrug-resistant and extensively drug-resistant tuberculosis. Int J Infect Dis 16: e391e396. [Google Scholar]
  15. Milewicz DM, Lorenz RG, Dermody TS, Brass LF, National Association of MD-PhD Programs Executive Committee; , 2015. Rescuing the physician-scientist workforce: the time for action is now. J Clin Invest 125: 37423747. [Google Scholar]
  16. NIH Advisory Group, 2014. Physician-Scientist Workforce Working Group Report. Available at: https://acd.od.nih.gov/documents/reports/PSW_Report_ACD_06042014.pdf. Accessed June 15, 2017.
  17. National Research Mentoring Network (NRMN), 2012. Mentoring Training for Clinical and Translational Researchers. Available at: https://nrmnet.net/. Accessed June 15, 2017.
  18. Powell K, , 2012. Publishing: foreign tongues. Nature 487: 129131. [Google Scholar]
  19. Friedrich MJ, , 2017. Fogarty International Center, a linchpin of global health research. JAMA 317: 21522153. [Google Scholar]
  20. Karim SSA, 2017. Closing the NIH Fogarty Center threatens US and global health. Lancet 390: 451. [Google Scholar]
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  • Received : 22 Aug 2017
  • Accepted : 26 Dec 2017
  • Published online : 05 Feb 2018

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