1921
Volume 98, Issue 5
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

Dengue fever (DF) is a mosquito-borne acute viral disease presenting with hemorrhagic manifestations in severe cases. Southeast Iran is in close proximity to Pakistan, an endemic country for DF. This cross-sectional study was conducted in the Sistan and Baluchestan province in the southeast of Iran to investigate possibility of DF (immunoglobulin M [IgM], immunoglobulin G [IgG], and nonstructural protein 1 [NS1] antigen tests) in 60 clinically suspected patients (April 2013 to August 2015). NS1 protein was detected in 5% ( = 3), at least one of the antibodies (IgM and/ or IgG) was detected in 11% ( = 7) of the samples. Five patients identified as of acutely infected. There was a simultaneous presence of NS1 protein and IgG or IgM antibodies in 4% ( = 2) of patients. Previous studies show establishment of potential vectors in this area. These evidences support the hypothesis that DF can be a health concern in Southeast Iran with potential future outbreaks.

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References

  1. WHO, 2009. Dengue: Guidelines for Diagnosis, Treatment, Prevention and Control: New Edition. Geneva: World Health Organization. WHO Guidelines Approved by the Guidelines Review Committee. Available at: http://www.who.int/tdr/publications/documents/dengue-diagnosis.pdf. Accessed June 13, 2017.
  2. WHO, 2013. Dengue Fever in Pakistan. WHO Surveillance, Forecasting and Response. Available at: http://www.emro.who.int/surveillance-forecasting-response/outbreaks/dengue-fever-in-pakistan.html. Accessed June 13, 2017.
  3. Cecilia D, 2014. Current status of dengue and chikungunya in India. WHO South-East Asia J Public Health 3: 2427.
    [Google Scholar]
  4. Elyan DS, Moustafa L, Noormal B, Jacobs JS, Aziz MA, Hassan KS, Wasfy MO, Monestersky JH, Oyofo BA, 2014. Serological evidence of flaviviruses infection among acute febrile illness patients in Afghanistan. J Infect Dev Ctries 8: 11761180.
    [Google Scholar]
  5. Mardani M, Abbasi F, Aghahasani M, Ghavam B, 2013. First Iranian imported case of dengue. Int J Prev Med 4: 10751077.
    [Google Scholar]
  6. Chinikar S et al., ., 2013. Preliminary study of dengue virus infection in Iran. Travel Med Infect Dis 11: 166169.
    [Google Scholar]
  7. Hii YL, Zhu H, Ng N, Ng LC, Rocklöv J, 2012. Forecast of dengue incidence using temperature and rainfall. PLoS Negl Trop Dis 6: e1908.
    [Google Scholar]
  8. Bostan N, Javed S, Nabgha-E-Amen, Eqani SA, Tahir F, Bokhari H, 2017. Dengue fever virus in Pakistan: effects of seasonal pattern and temperature change on distribution of vector and virus. Rev Med Virol 27: e1899.
    [Google Scholar]
  9. Nunes MR et al., ., 2014. Air travel is associated with intracontinental spread of dengue virus serotypes 1–3 in Brazil. PLoS Negl Trop Dis 8: e2769.
    [Google Scholar]
  10. Stoddard ST, Morrison AC, Vazquez-Prokopec GM, Paz Soldan V, Kochel TJ, Kitron U, Elder JP, Scott TW, 2009. The role of human movement in the transmission of vector-borne pathogens. PLoS Negl Trop Dis 3: e481.
    [Google Scholar]
  11. Wesolowski A, Qureshi T, Boni MF, Sundsøy PR, Johansson MA, Rasheed SB, Engø-Monsen K, Buckee CO, 2015. Impact of human mobility on the emergence of dengue epidemics in Pakistan. Proc Natl Acad Sci USA 112: 1188711892.
    [Google Scholar]
  12. Zubair M, Ashraf M, Ahsan A, Nazir NU, Hanif H, Khan HA, 2016. Dengue viral infections in Pakistan and other Asian countries: a comprehensive review. J Pak Med Assoc 66: 884888.
    [Google Scholar]
  13. Ali A et al., ., 2013. Seroepidemiology of dengue fever in Khyber Pakhtunkhawa, Pakistan. Int J Infect Dis 17: e518e523.
    [Google Scholar]
  14. Chinikar S, Javadi A, Ataei B, Shakeri H, Moradi M, Mostafavi E, Ghiasi SM, 2012. Detection of West Nile virus genome and specific antibodies in Iranian encephalitis patients. Epidemiol Infect 140: 15251529.
    [Google Scholar]
  15. Aghaie A, Aaskov J, Chinikar S, Niedrig M, Banazadeh S, Mohammadpour HK, 2016. Frequency of West Nile virus infection in Iranian blood donors. Indian J Hematol Blood Transfus 32: 343346.
    [Google Scholar]
  16. Chinikar S, Shah-Hosseini N, Mostafavi E, Moradi M, Khakifirouz S, Jalali T, Goya MM, Shirzadi MR, Zainali M, Fooks AR, 2013. Seroprevalence of West Nile virus in Iran. Vector Borne Zoonotic Dis 13: 586589.
    [Google Scholar]
  17. Doosti S, Yaghoobi-Ershadi MR, Schaffner F, Moosa-Kazemi SH, Akbarzadeh K, Gooya MM, Vatandoost H, Shirzadi MR, Mosta-Favi E, 2016. Mosquito surveillance and the first record of the invasive mosquito species Aedes (Stegomyia) albopictus (Skuse) (Diptera: Culicidae) in southern Iran. Iran J Public Health 45: 10641073.
    [Google Scholar]
  18. Yaghoobi-Ershadi MR, Doosti S, Schaffner F, Moosa-Kazemi SH, Akbarzadeh K, Yaghoobi-Ershadi N, 2017. Morphological studies on adult mosquitoes (Diptera: Culicidae) and first report of the potential Zika virus vector Aedes (Stegomyia) unilineatus (Theobald, 1906) in Iran. Bull Soc Pathol Exot 110: 116121.
    [Google Scholar]
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  • Received : 10 Aug 2017
  • Accepted : 09 Oct 2017
  • Published online : 19 Mar 2018
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