Prostatic Abscess due to Burkholderia pseudomallei: Facilitating Diagnosis to Optimize Management

Jowita Kozlowska; Simon Smith; Jay Roberts; Simon Pridgeon; Josh Hanson

doi:10.4269/ajtmh.17-0633

ISSN: 0002-9637
E-ISSN: 1476-1645

Download

f Prostatic Abscess due to Burkholderia pseudomallei: Facilitating Diagnosis to Optimize Management

Jowita Kozlowska¹, Simon Smith^1,2, Jay Roberts¹, Simon Pridgeon¹, Josh Hanson^1,3,4
View Affiliations Hide Affiliations

Affiliations: ¹ Cairns Hospital, Cairns, Queensland, Australia; ² James Cook University, Cairns, Queensland, Australia; ³ The Kirby Institute, University of New South Wales, Sydney, Australia; ⁴ Menzies School of Health Research, Darwin, Australia

*Address correspondence to Josh Hanson, The Kirby Institute, Wallace Wurth Building, High Street, Kensington NSW 2052, Australia. E-mail: jhanson@kirby.unsw.edu.au
fn1Authors’ addresses: Jowita Kozlowska and Simon Smith, Department of Medicine, Cairns Hospital, Cairns, Queensland, Australia, E-mails: jowitakozl@gmail.com and simon.smith2@health.qld.gov.au. Simon Smith, Department of Medicine, Cairns Hospital, The Esplanade, Cairns, Queensland, Australia, E-mail: simon.smith2@health.qld.gov.au. Jay Roberts and Simon Pridgeon, Department of Urology, Cairns Hospital, Cairns, Queensland, Australia, E-mails: jay.roberts@health.qld.gov.au and simon.pridgeon@health.qld.gov.au. Josh Hanson, The Director’s Unit, The Kirby Institute, University of New South Wales, Sydney, New South Wales, Australia, and Cairns Hospital, General Medicine, Cairns, Queensland, Australia, E-mail: jhanson@kirby.unsw.edu.au.
Publisher: The American Society of Tropical Medicine and Hygiene
Source: The American Journal of Tropical Medicine and Hygiene, Volume 98, Issue 1, 10 Jan 2018, p. 227 - 230
DOI: https://doi.org/10.4269/ajtmh.17-0633

Abstract

Abstract.

Prostatic involvement is common in men with melioidosis. Indeed, some clinicians recommend radiological screening of all male patients as an undrained prostatic abscess may result in relapse of this potentially fatal disease. However, sophisticated medical imaging is frequently unavailable in the remote and resource-poor locations where patients are managed. In this retrospective study from Queensland, Australia, 22/144 (15%) men with melioidosis had a radiologically confirmed prostatic abscess. The absence of urinary symptoms had a negative predictive value (NPV) (95% confidence interval [CI]) for prostatic abscess of 96% (90–99%), whereas a urinary leukocyte count of < 50 × 106/L had an NPV (95% CI) of 100% (94–100%). A simple clinical history and basic laboratory investigations appear to exclude significant prostatic involvement relatively reliably and might be used to identify patients in whom radiological evaluation of the prostate is unnecessary. This may be particularly helpful in locations where radiological support is limited.

Article metrics loading...

The graphs shown below represent data from March 2017

/content/journals/10.4269/ajtmh.17-0633

2017-10-30

2020-09-23

From This Site

/content/journals/10.4269/ajtmh.17-0633

dcterms_title,dcterms_subject,pub_keyword

10

5

Full text loading...

/deliver/fulltext/14761645/98/1/tpmd170633.html?itemId=/content/journals/10.4269/ajtmh.17-0633&mimeType=html&fmt=ahah

References

Wiersinga WJ, Currie BJ, Peacock SJ, 2012. Melioidosis. N Engl J Med 367: 1035–1044.
[Google Scholar]
Cheng AC, Currie BJ, 2005. Melioidosis: epidemiology, pathophysiology, and management. Clin Microbiol Rev 18: 383–416.
[Google Scholar]
Currie BJ, Ward L, Cheng AC, 2010. The epidemiology and clinical spectrum of melioidosis: 540 cases from the 20 year Darwin prospective study. PLoS Negl Trop Dis 4: e900.
[Google Scholar]
Stewart JD, Smith S, Binotto E, McBride WJ, Currie BJ, Hanson J, 2017. The epidemiology and clinical features of melioidosis in far north Queensland: implications for patient management. PLoS Negl Trop Dis 11: e0005411.
[Google Scholar]
Morse LP, Moller CC, Harvey E, Ward L, Cheng AC, Carson PJ, Currie BJ, 2009. Prostatic abscess due to Burkholderia pseudomallei: 81 cases from a 19-year prospective melioidosis study. J Urol 182: 542–547, discussion 547.
[Google Scholar]
Ng TH, How SH, Amran AR, Razali MR, Kuan YC, 2009. Melioidotic prostatic abscess in Pahang. Singapore Med J 50: 385–589.
[Google Scholar]
Kessler C, Bauer SJ, 2012. Utility of the digital rectal examination in the emergency department: a review. J Emerg Med 43: 1196–1204.
[Google Scholar]
Chong Vh VH, Sharif F, Bickle I, 2014. Urogenital melioidosis: a review of clinical presentations, characteristic and outcomes. Med J Malaysia 69: 257–260.
[Google Scholar]
Chou DW, Chung KM, Chen CH, Cheung BM, 2007. Bacteremic melioidosis in southern Taiwan: clinical characteristics and outcome. J Formos Med Assoc 106: 1013–1022.
[Google Scholar]
Punyagupta S, 1989. Meliodosis. Review of 686 Cases and Presentation of a New Clinical Classification. Bangkok, Thailand: Bangkok Medical Publisher.
Dhiensiri T, Eua-Ananta Y, 1995. Visceral abscess in melioidosis. J Med Assoc Thai 78: 225–231.
[Google Scholar]
Vaccaro JA, Belville WD, Kiesling VJ Jr, Davis R, 1986. Prostatic abscess: computerized tomography scanning as an aid to diagnosis and treatment. J Urol 136: 1318–1319.
[Google Scholar]
Pinto A, Pinto F, Faggian A, Rubini G, Caranci F, Macarini L, Genovese EA, Brunese L, 2013. Sources of error in emergency ultrasonography. Crit Ultrasound J 5 (Suppl 1): S1.
[Google Scholar]
Sawyer RG et al., 2015. Trial of short-course antimicrobial therapy for intraabdominal infection. N Engl J Med 372: 1996–2005.
[Google Scholar]
Limmathurotsakul D, Chaowagul W, Chierakul W, Stepniewska K, Maharjan B, Wuthiekanun V, White NJ, Day NP, Peacock SJ, 2006. Risk factors for recurrent melioidosis in northeast Thailand. Clin Infect Dis 43: 979–986.
[Google Scholar]

http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.17-0633

Prostatic Abscess due to Burkholderia pseudomallei: Facilitating Diagnosis to Optimize Management

The American Journal of Tropical Medicine and Hygiene 98, 227 (2018); https://doi.org/10.4269/ajtmh.17-0633

/content/journals/10.4269/ajtmh.17-0633

Data & Media loading...

Received : 09 Aug 2017
Accepted : 02 Sep 2017
Published online : 30 Oct 2017

f Prostatic Abscess due to Burkholderia pseudomallei: Facilitating Diagnosis to Optimize Management

Abstract

From This Site

Most Cited This Month

Techniques for Hemagglutination and Hemagglutination-Inhibition with Arthropod-Borne Viruses

Identification of Single Specimens of the Anopheles Gambiae Complex by the Polymerase Chain Reaction

The Epidemiology of Dengue in the Americas Over the Last Three Decades: A Worrisome Reality

Vivax Malaria: Neglected and Not Benign

Research on Dengue during World War II 1

A Neurotropic Virus Isolated from the Blood of a Native of Uganda 1

A Review of Malaria Diagnostic Tools: Microscopy and Rapid Diagnostic Test (RDT)

Ethics and Best Practice Guidelines for Training Experiences in Global Health

Economic Impact of Dengue Illness in the Americas

The economic burden of malaria