Volume 97, Issue 6
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



Schistosomiasis causes mainly hepatic and genitourinary damage. Although lung nodules have been commonly described in acute phase, they are presumably underdiagnosed in chronic schistosomiasis. We previously reported a series of patients with chronic pulmonary schistosomiasis confirmed by the histological examination of the lung biopsies. In the present work, we retrospectively tested an in-house real-time polymerase chain reaction for (currently validated for diagnosis on stool and on urine) in the bronchoalveolar lavage (BAL) of a couple of those patients, and both resulted positive. The possibility of testing BAL with molecular methods targeting a wide spectrum of pathogens, including parasites, is appealing. Further studies are needed to validate this technique that might reduce unnecessary biopsies.


Article metrics loading...

The graphs shown below represent data from March 2017
Loading full text...

Full text loading...



  1. Colley DG, Bustinduy AL, Secor WE, King CH, 2014. Human schistosomiasis. Lancet 383: 22532264.
    [Google Scholar]
  2. Niemann T, Marti HP, Duhnsen SH, Bongartz G, 2010. Pulmonary schistosomiasis–imaging features. J Radiol Case Rep 4: 3743.
    [Google Scholar]
  3. Ross AG, Vickers D, Olds GR, Shah SM, McManus DP, 2007. Katayama syndrome. Lancet Infect Dis 7: 218224.
    [Google Scholar]
  4. Papamatheakis DG, Mocumbi AO, Kim NH, Mandel J, 2014. Schistosomiasis associated pulmonary hypertension. Pulm Circ 4: 596611.
    [Google Scholar]
  5. Schwartz E, 2002. Pulmonary schistosomiasis. Clin Chest Med 23: 433443.
    [Google Scholar]
  6. Gobbi F et al., 2017. Pulmonary nodules in African migrants caused by chronic schistosomiasis. Lancet Infect Dis 17: e159e165.
    [Google Scholar]
  7. Obeng BB et al., 2008. Application of a circulating-cathodic-antigen (CCA) strip test and real-time PCR, in comparison with microscopy, for the detection of Schistosoma haematobium in urine samples from Ghana. Ann Trop Med Parasitol 102: 625633.
    [Google Scholar]
  8. Castelli F, Sulis G, 2017. Migration and infectious diseases. Clin Microbiol Infect 23: 283289.
    [Google Scholar]
  9. Kunst H, Mack D, Kon OM, Banerjee AK, Chiodini P, Grant A, 2011. Parasitic infections of the lung: a guide for the respiratory physician. Thorax 66: 528536.
    [Google Scholar]
  10. Utzinger J, Becker SL, van Lieshout L, van Dam GJ, Knopp S, 2015. New diagnostic tools in schistosomiasis. Clin Microbiol Infect 21: 529542.
    [Google Scholar]

Data & Media loading...

  • Received : 23 Jun 2017
  • Accepted : 22 Aug 2017
  • Published online : 09 Oct 2017
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error