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image of Real-Time Polymerase Chain Reaction Assay on Bronchoalveolar Lavage: An Alternative Method for Diagnosing Chronic Pulmonary Schistosomiasis?
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645
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Abstract

Schistosomiasis causes mainly hepatic and genitourinary damage. Although lung nodules have been commonly described in acute phase, they are presumably underdiagnosed in chronic schistosomiasis. We previously reported a series of patients with chronic pulmonary schistosomiasis confirmed by the histological examination of the lung biopsies. In the present work, we retrospectively tested an in-house real-time polymerase chain reaction for (currently validated for diagnosis on stool and on urine) in the bronchoalveolar lavage (BAL) of a couple of those patients, and both resulted positive. The possibility of testing BAL with molecular methods targeting a wild spectrum of pathogens, including parasites, is appealing. Further studies are needed to validate this technique that might reduce unnecessary biopsies.

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/content/journals/10.4269/ajtmh.17-0499
2017-10-09
2017-11-24
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http://instance.metastore.ingenta.com/content/journals/10.4269/ajtmh.17-0499
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  • Published online : 09 Oct 2017
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