1921
Volume 98, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645

Abstract

Abstract.

Intestinal capillariasis caused by , a fish-borne nematode, is an important, emerging zoonotic helminthiasis. Cases may be fatal if suitable treatment is not administered in time. We reported a hospital-based study of 85 cases in Thailand, most of which were in the northeast. All patients had a history of eating raw or insufficiently cooked fresh water fish or prawns. The clinical manifestations are characterized by chronic diarrhea, borborygmi, abdominal pain, marked weight loss, muscle weakness, fatigue, dizziness, anorexia, and edema, as well as protein and electrolyte loss. Fecal examination revealed in all patients. Although 16 of the total of 85 (18.8%) cases were initially found to be negative for using fecal examination, further examination using an immunoblotting technique found them to be positive for the IgG antibody against larval antigen. One day after administration of 400 mg of albendazole, eggs and/or larvae and/or adult were found in 16 fecal samples. After treatment with mebendazole (200 mg twice a day for 30 days) or albendazole (200 mg twice a day for 10 days), all 85 patients recovered. The potential clues for diagnosis are clinical manifestations, history of eating raw contaminated food, and positive serological test, and fecal examinations under professional. Administration of anthelminthic drugs stimulates the excretion of larvae, eggs, and/or adult worms and can be used as a supportive method for the diagnosis of intestinal capillariasis in areas where serological test is not available.

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References

  1. McCarthy J, Moore TA, , 2000. Emerging helminth zoonoses. Int J Parasitol 30: 13511360. [Google Scholar]
  2. Chitwood MB, Valesquez C, Salazar NG, , 1968. Capillaria philippinensis sp. n. (Nematoda: Trichinellida), from the intestine of man in the Philippines. J Parasitol 54: 368371. [Google Scholar]
  3. Beaver PC, Jung RC, Cupp EW, , 1984. Aphasmid nematodes. Beaver PC, Jung RC, Cupp EW, eds. Clinical Parasitology, 9th edition. Philadelphia, PA: Lea & Febiger, 231252.
  4. Belizario VY, Jr Totañes G, de Leon FI, Migriño WU, JR, Jr Macasaet LY, , 2010. Intestinal capillariasis, western Mindanao, the Philippines. Emerg Infect Dis 16: 736738. [Google Scholar]
  5. Chichino G, Bernuzzi AM, Bruno A, Cevini C, Atzori C, Malfitano A, Scaglia M, , 1992. Intestinal capillariasis (Capillaria philippinensis) acquired in Indonesia: a case report. Am J Trop Med Hyg 47: 112. [Google Scholar]
  6. Soukhathammavong P, 2008. Three cases of intestinal capillariasis in Lao People’s Democratic Republic. Am J Trop Med Hyg 79: 735738. [Google Scholar]
  7. Cross JH, , 1992. Intestinal capillariasis. Clin Microbiol Rev 5: 120129. [Google Scholar]
  8. Chen CY, Hsieh WC, Lin JT, Liu MC, , 1989. Intestinal capillariasis: report of a case. Taiwan Yi Xue Hui Za Zhi 88: 617620. [Google Scholar]
  9. Kang G, Mathan M, Ramakrishna BS, Mathai E, Sarada V, , 1994. Human intestinal capillariasis: first report from India. Trans R Soc Trop Med Hyg 88: 204. [Google Scholar]
  10. Hoghooghi-Rad N, Maraghi S, Narenj-Zadeh A, , 1987. Capillaria philippinensis infection in Khoozestan province, Iran: case report. Am J Trop Med Hyg 37: 135137. [Google Scholar]
  11. Youssef FG, Mikhail EM, Mansour NS, , 1989. Intestinal capillariasis in Egypt: a case report. Am J Trop Med Hyg 40: 195196. [Google Scholar]
  12. Mansour NS, Anis MH, Mikhail EM, , 1990. Human intestinal capillariasis in Egypt. Trans R Soc Trop Med Hyg 84: 114. [Google Scholar]
  13. Dronda F, Chaves F, Sanz A, Lopez-Velez R, , 1993. Human intestinal capillariasis in an area of nonendemicity: case report and review. Clin Infect Dis 17: 909912. [Google Scholar]
  14. Austin DN, Mikhail MG, Chiodini PL, Murray-Lyon IM, , 1999. Intestinal capillariasis acquired in Egypt. Eur J Gastroenterol Hepatol 11: 935936. [Google Scholar]
  15. Pradatsundarasar A, Pecharanond K, Chintanawongs C, Ungthavorn P, , 1973. The first case of intestinal capillariasis in Thailand. Southeast Asian J Trop Med Public Health 4: 131134. [Google Scholar]
  16. Sanpakit S, Suksungvol S, Bhaibulaya M, , 1974. Intestinal capiliariasis from Saraburi province, Thailand: report on the second case. J Med Assoc Thai 57: 458460. [Google Scholar]
  17. Prakitrittranon W, Eua-Ananta YU, Dhiensiri T, Bhaibulaya M, , 1980. Intestinal capillariasis from Maha Sarakham province, northeast Thailand: report of a case. Southeast Asian J Trop Med Public Health 11: 496497. [Google Scholar]
  18. Benjanuwattar T, Morakote N, Somboon P, Sivasomboon B, , 1990. Intestinal capillariasis: indigenous cases from Chiang Mai and Phayao provinces, Thailand. J Med Assoc Thai 73: 414417. [Google Scholar]
  19. Chunlertrith K, Mairiang P, Sukeepaisarnjaroen W, , 1992. Intestinal capillariasis: a cause of chronic diarrhea and hypoalbuminemia. Southeast Asian J Trop Med Public Health 23: 433436. [Google Scholar]
  20. Sangchan A, Wongsaensook A, Kularbkaew C, Sawanyawisuth K, Sukeepaisarnjaroen W, Mairiang P, , 2007. The endoscopic-pathologic findings in intestinal capillariais: a case report. J Med Assoc Thai 90: 175178. [Google Scholar]
  21. Saichua P, Nithikathkul C, Kaewpitoon N, , 2008. Human intestinal capillariasis in Thailand. World J Gastroenterol 14: 506510. [Google Scholar]
  22. Elkins DB, Haswell-Elkins M, Anderson RM, , 1986. The epidemiology and control of intestinal helminths in the Pulicat Lake region of southern India. I. Study design and pre- and post-treatment observations on Ascaris lumbricoides infection. Trans R Soc Trop Med Hyg 80: 774792. [Google Scholar]
  23. Intapan PM, Maleewong W, Sukeepaisarnjaroen W, Morakote N, , 2006. Potential use of Trichinella spiralis antigen for serodiagnosis of human capillariasis philippinensis by immunoblot analysis. Parasitol Res 98: 227231. [Google Scholar]
  24. Lu LH, Lin MR, Choi WM, Hwang KP, Hsu YH, Bair MJ, Liu JD, Wang TE, Liu TP, Chung WC, , 2006. Human intestinal capillariasis (Capillaria philippinensis) in Taiwan. Am J Trop Med Hyg 74: 810813. [Google Scholar]
  25. Dorny P, Praet N, Deckers N, Gabriel S, , 2009. Emerging food-borne parasites. Vet Parasitol 163: 196206. [Google Scholar]
  26. Paulino GB, Jr Wittenberg J, , 1973. Intestinal capillariasis: a new cause of a malabsorption pattern. Am J Roentgenol Radium Ther Nucl Med 117: 340345. [Google Scholar]
  27. Kunaratanapruk S, Iam-Ong S, Chatsirimongkol C, , 1981. Intestinal capillariasis: the first endemic in Thailand. Ramathibodi Med J 4: 209213. [Google Scholar]
  28. Kunaratanapruk S, Iam-Ong S, Chatsirimongkol C, Dhirasut C, Laohanuwat C, , 1983. Intestinal capillariasis: a report of 100 cases. Ramathibodi Med J 6: 253258. [Google Scholar]
  29. Pathanacharoen S, Tansuphaswaddikul S, Manutstitt S, Thanangkul B, , 1983. Intestinal capillariasis: a review and report of three cases. Ramathibodi Med J 6: 277283. [Google Scholar]
  30. Bhaibulaya M, Benjapong W, Noeypatimanond S, , 1977. Infection of Capillaria philippinensis in man from Phetchabun province, northern Thailand: a report of the fifth case. J Med Assoc Thai 60: 507509. [Google Scholar]
  31. Wilairatana P, , 1994. Capillariasis with chronic intestinal pseudo-obstruction. Southeast Asian J Trop Med Public Health 25: 600602. [Google Scholar]
  32. Wongsawasdi L, Ukarapol N, Lertprasertsuk N, , 2002. The endoscopic diagnosis of intestinal capillariasis in a child: a case report. Southeast Asian J Trop Med Public Health 33: 730732. [Google Scholar]
  33. Bhaibulaya M, Indra-Ngarm S, Ananthapruti M, , 1979. Freshwater fishes of Thailand as experimental intermediate hosts for Capillaria philippinensis. Int J Parasitol 9: 105108. [Google Scholar]
  34. Limsrivilai J, Pongprasobchai S, Apisarnthanarak P, Manatsathit S, , 2014. Intestinal capillariasis in the 21st century: clinical presentations and role of endoscopy and imaging. BMC Gastroenterol 14: 207. [Google Scholar]
  35. Rana SS, Bhasin DK, Bhatti HS, Gupta K, Gupta R, Nada R, Nagi B, Sinha SK, Singh K, , 2009. Human intestinal capillariasis: diagnosis by jejunal fluid analysis obtained at enteroscopy and reversal of subtotal villous atrophy after treatment. Endoscopy 41 (Suppl 2): E102E103. [Google Scholar]
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  • Received : 14 Jun 2017
  • Accepted : 31 Aug 2017

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