Volume 98, Issue 1
  • ISSN: 0002-9637
  • E-ISSN: 1476-1645



, a spotted fever group rickettsial pathogen, causes a syndrome consisting of scalp eschar and neck lymphadenopathy following tick bite. We analyzed the histologic skin reaction in the eschar, showing a prominent eosinophilic infiltration, as well as the presence of B lymphocytes and CD4- and CD8-positive T cells. Examination of the serum cytokine responses over time demonstrated an initial proinflammatory cytokine elevation followed by normalization.


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  • Received : 18 May 2017
  • Accepted : 28 Aug 2017
  • Published online : 23 Oct 2017

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